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Болюсы Хуато
Лекарственный препарат Болюсы Хуато - коррекция недостаточности мозгового кровообращения возрастного и сосудистого генеза, лечения и реабилитации после инсульта.

Препарат Традиционной Китайской Медицины.

Зарегистрирован компанией Дао-Фарм в странах: Беларусь, Грузия, Россия.

Единственный производитель: Фармацевтическая фабрика “Байюньшань Цисин Ltd”, г. Гуанчжоу, Китай

При поддержке Фонда содействия изучению и внедрению лекарственных средств растительного, животного и минерального происхождения



The Protective Effect Of Huatuo Zaizao Pills Against Neuronal Injury On Focal Cerebral Ischemia In R

OBJECTIVE To investigate the protective effects of Huatuo Zaizao pills(HTZZ) to neuron and glial cells in the "penumbra" area on focal cerebral ischemia-reperfusion(FCI- R) injury in rats. METHODS The FCI - R model with thread embolism of middle cerebral artery occlusion (MCAO) in rats was made.The neurological deficit score(NDS) was assessed.TTC staining were used to evaluate the infarct volume of injured rats. Adopting immunohistochemistry method to detect the changes of neuron - specific enolase (NSE) and glial fibrillary acidic protein (GFAP) expression at the time of 22 h,70 h after MCAO. RESULTS Compared with those in the control group, the NDS were all significantly increased( P < 0.05) ;the infarct volume were significantly decreased(P < 0.05) ;the level of NSE expression in the "penumbra" area were all significantly increased( P < 0.05) and the level of GFAP expression in the "penumbra" area were significantly decreased( P < 0.05 ) in the HTZZ - treated group at 22 h, 70 h after FCI - R ( P < 0.05 ) . The level of GFAP expression at 70 h after FCI - R were slightly increased ( P > 0.05)than that at 22 h after FCI - R in the HTZZ - treated group. CONCLUSION The result shows that HTZZ has significant protective effects to neuron and glial cells in the "penumbra" area in FCI- R rats.

Источник: www.shvoong.com
 


                          


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